Latest Life Science White Papers https://www.news-medical.net/ en-GB Discover how to utilize process Raman analysis for accurate protein quantification in downstream biopharmaceutical processes. https://www.news-medical.net/whitepaper/20241107/Accurate-protein-quantification-with-process-Raman-analysis.aspx https://www.news-medical.net/whitepaper/20241107/Accurate-protein-quantification-with-process-Raman-analysis.aspx Mon, 09 Sep 2024 06:14:16 -0500 In this article, InProcess-LSP compares spatially resolved DLS and conventional DLS. https://www.news-medical.net/whitepaper/20241106/Spatially-resolved-DLS-versus-conventional-DLS.aspx https://www.news-medical.net/whitepaper/20241106/Spatially-resolved-DLS-versus-conventional-DLS.aspx Tue, 05 Nov 2024 03:26:30 -0500 Nano emulsions are widespread as intermediate or end-products in food, cosmetics, pharmaceutical and chemical industries. https://www.news-medical.net/whitepaper/20241106/Real-time-droplet-size-monitoring-of-nano-emulsions-during-high-pressure-homogenization.aspx https://www.news-medical.net/whitepaper/20241106/Real-time-droplet-size-monitoring-of-nano-emulsions-during-high-pressure-homogenization.aspx Tue, 05 Nov 2024 02:57:31 -0500 In this article, InProcess demonstrates the potential of in-line nanoparticle size measurements using the NanoFlowSizer (NFS) as a PAT method. https://www.news-medical.net/whitepaper/20241106/Real-time-process-control-in-nanodispersion-manufacturing-via-continuous-nanoparticle-size-monitoring.aspx https://www.news-medical.net/whitepaper/20241106/Real-time-process-control-in-nanodispersion-manufacturing-via-continuous-nanoparticle-size-monitoring.aspx Tue, 05 Nov 2024 03:20:16 -0500 In this article, InProcess describes improved inline and off-line nanoparticle sizing techniques with spatially resolved DLS. https://www.news-medical.net/whitepaper/20241106/PhaSR-DLSe28099-A-new-advancement-in-spatially-resolved-DLS-for-enhanced-inline-and-off-line-nanoparticle-sizing.aspx https://www.news-medical.net/whitepaper/20241106/PhaSR-DLSe28099-A-new-advancement-in-spatially-resolved-DLS-for-enhanced-inline-and-off-line-nanoparticle-sizing.aspx Tue, 05 Nov 2024 02:36:50 -0500 InProcess-LSP are a young organization, founded in 2014, they have since emerged as providers of groundbreaking process analytical technology for nanoparticle characterization. This article provides a brief background to the company and their products. https://www.news-medical.net/whitepaper/20241106/InProcess-LSP-Providers-of-groundbreaking-PAT-for-nanoparticle-characterization.aspx https://www.news-medical.net/whitepaper/20241106/InProcess-LSP-Providers-of-groundbreaking-PAT-for-nanoparticle-characterization.aspx Wed, 30 Oct 2024 03:36:00 -0500 Lipid-based nanoparticles have emerged as highly useful particles in the pharmaceutical industry. However, their manufacturing involves complex processes and in-process monitoring, such as inline size characterization, is becoming more and more important. https://www.news-medical.net/whitepaper/20241106/Lipid-based-nanoparticles-Manufacturing-and-inline-size-characterization.aspx https://www.news-medical.net/whitepaper/20241106/Lipid-based-nanoparticles-Manufacturing-and-inline-size-characterization.aspx Wed, 30 Oct 2024 04:11:08 -0500 Dynamic Light Scattering is commonly used to rapidly measure the hydrodynamic size and size dispersity of nanoparticles in suspension. Several commercial DLS instruments exist, using a range of illumination wavelengths and detection angles. https://www.news-medical.net/whitepaper/20241106/How-do-results-from-different-dynamic-light-scattering-instruments-compare.aspx https://www.news-medical.net/whitepaper/20241106/How-do-results-from-different-dynamic-light-scattering-instruments-compare.aspx Wed, 30 Oct 2024 03:35:03 -0500 This article explores how you can measure particle size CQAs in (sterile) pharmaceutical packaging, and discusses non-invasive measurements using SR-DLS. https://www.news-medical.net/whitepaper/20241106/How-can-you-measure-particle-size-CQAs-in-(sterile)-pharmaceutical-packaging-e28093-non-invasive-measurements-using-SR-DLS.aspx https://www.news-medical.net/whitepaper/20241106/How-can-you-measure-particle-size-CQAs-in-(sterile)-pharmaceutical-packaging-e28093-non-invasive-measurements-using-SR-DLS.aspx Wed, 30 Oct 2024 03:33:36 -0500 Nanoparticles have once again reached the spotlight, this time as a critical tool to combat the spread of covid-19. In this particular case, messenger ribonucleic acid (mRNA) encapsulated in lipid nanoparticles (LNPs) have been successfully manufactured, distributed and administered to populations throughout the world. https://www.news-medical.net/whitepaper/20241106/Continuous-processing-and-enhanced-control-of-lipid-based-nanoparticles-LNPs-and-liposomes.aspx https://www.news-medical.net/whitepaper/20241106/Continuous-processing-and-enhanced-control-of-lipid-based-nanoparticles-LNPs-and-liposomes.aspx Wed, 30 Oct 2024 03:30:55 -0500 This article details how the nanoflowsizer is used for continuous size monitoring of turbid titanium dioxide nanosuspensions. https://www.news-medical.net/whitepaper/20241106/Continuous-size-monitoring-of-turbid-titanium-dioxide-nanosuspensions-with-the-Nanoflowsizer.aspx https://www.news-medical.net/whitepaper/20241106/Continuous-size-monitoring-of-turbid-titanium-dioxide-nanosuspensions-with-the-Nanoflowsizer.aspx Wed, 30 Oct 2024 03:32:15 -0500 This article discusses continuous manufacturing and the increasing interest of this over traditional batch processing for nanoparticle drug delivery systems. https://www.news-medical.net/whitepaper/20241106/Continuous-manufacturing-of-liposomal-products.aspx https://www.news-medical.net/whitepaper/20241106/Continuous-manufacturing-of-liposomal-products.aspx Wed, 30 Oct 2024 03:28:38 -0500 The size and size distribution of low turbidity suspensions in various (bio)pharmaceutical products, including liposomes, lipid nanoparticles, recombinant proteins, and antibodies, plays a significant role in their pharmacokinetic and pharmacodynamic profile in vivo. These factors directly influence therapeutic efficacy, immunogenicity, and safety. Consequently, particle size is considered one of the critical quality attributes for such products. https://www.news-medical.net/whitepaper/20241106/Continuous-inline-size-monitoring-of-low-turbidity-suspensions-under-flow-in-biopharmaceutical-processes.aspx https://www.news-medical.net/whitepaper/20241106/Continuous-inline-size-monitoring-of-low-turbidity-suspensions-under-flow-in-biopharmaceutical-processes.aspx Wed, 30 Oct 2024 03:27:11 -0500 Aggregates and small fractions of ‘oversized’ particles can significantly impact the quality and safety of nanosuspensions. https://www.news-medical.net/whitepaper/20241106/A-new-method-for-non-invasive-or-inline-detection-of-aggregates-and-oversized-particles-in-nanosuspensions.aspx https://www.news-medical.net/whitepaper/20241106/A-new-method-for-non-invasive-or-inline-detection-of-aggregates-and-oversized-particles-in-nanosuspensions.aspx Wed, 30 Oct 2024 03:17:42 -0500 Discover how SIFT-MS technology enables rapid, sensitive, and efficient detection of ethylene oxide in Polysorbate 80. https://www.news-medical.net/whitepaper/20241106/Rapid-Ethylene-Oxide-Detection-in-Polysorbate-80-Using-SIFT-MS.aspx https://www.news-medical.net/whitepaper/20241106/Rapid-Ethylene-Oxide-Detection-in-Polysorbate-80-Using-SIFT-MS.aspx Fri, 25 Oct 2024 10:51:21 -0500 Learn how SIFT-MS streamlines nitrosamine analysis in drug products, delivers sensitive detection with three times the throughput of traditional methods. https://www.news-medical.net/whitepaper/20241106/Throughput-nitrosamine-analysis-in-drug-products-using-SIFT-MS.aspx https://www.news-medical.net/whitepaper/20241106/Throughput-nitrosamine-analysis-in-drug-products-using-SIFT-MS.aspx Fri, 25 Oct 2024 10:51:21 -0500 The benefits of upgrading outdated LIMS systems to improve efficiency, accuracy, and compliance. https://www.news-medical.net/whitepaper/20241017/The-hidden-costs-of-outdated-LIMS-systems.aspx https://www.news-medical.net/whitepaper/20241017/The-hidden-costs-of-outdated-LIMS-systems.aspx Wed, 09 Oct 2024 08:32:46 -0500 Explore how TA Instruments' RS-DSC enables rapid thermal stability screening of biologic drugs. https://www.news-medical.net/whitepaper/20241010/High-throughput-thermal-stability-screening-of-biologic-drugs-with-RS-DSC-technology.aspx https://www.news-medical.net/whitepaper/20241010/High-throughput-thermal-stability-screening-of-biologic-drugs-with-RS-DSC-technology.aspx Fri, 27 Sep 2024 10:50:39 -0500 Learn how TA Instruments' RS-DSC enables rapid thermal stability screening of monoclonal antibody drug products. https://www.news-medical.net/whitepaper/20241010/Rapid-thermal-stability-screening-of-monoclonal-antibody-drug-products-with-RS-DSC.aspx https://www.news-medical.net/whitepaper/20241010/Rapid-thermal-stability-screening-of-monoclonal-antibody-drug-products-with-RS-DSC.aspx Fri, 27 Sep 2024 10:50:39 -0500 Preventing repetitive strain injuries in laboratories is essential. Ergonomic practices and automated solutions can enhance workplace safety and health. https://www.news-medical.net/whitepaper/20241008/Repetitive-strain-injuries-The-hidden-danger-in-laboratory-work.aspx https://www.news-medical.net/whitepaper/20241008/Repetitive-strain-injuries-The-hidden-danger-in-laboratory-work.aspx Mon, 02 Sep 2024 12:01:43 -0500