Latest Life Science News https://www.news-medical.net/ en-GB University of Queensland researchers have developed a new class of oral painkillers to suppress chronic abdominal pain that is based on the peptide hormone oxytocin that drives childbirth contractions. https://www.news-medical.net/news/20241118/New-oral-painkiller-developed-for-chronic-abdominal-pain.aspx https://www.news-medical.net/news/20241118/New-oral-painkiller-developed-for-chronic-abdominal-pain.aspx#comment https://www.news-medical.net/post.aspx?id=0a3129e3-96a3-49f7-b6fa-1ed6ccf4d769 Mon, 18 Nov 2024 05:48:45 -0500 Researchers developed a barcoded directed evolution system for engineered virus-like particles (eVLPs), creating a fifth-generation (v5) eVLP with enhanced production, transduction, and gene-editing efficiency. This system could pave the way for improved gene delivery vehicles in therapeutic applications. https://www.news-medical.net/news/20241117/Engineered-virus-like-particles-evolve-for-superior-gene-delivery-efficiency.aspx https://www.news-medical.net/news/20241117/Engineered-virus-like-particles-evolve-for-superior-gene-delivery-efficiency.aspx#comment https://www.news-medical.net/post.aspx?id=f3a01f36-c360-4cbe-92e3-e5c78e038125 Sun, 17 Nov 2024 23:12:00 -0500 Researchers at Helmholtz Munich, in collaboration with colleagues at Tohoku University, have identified a specific redox protein as a critical regulator of ferroptosis - a form of regulated oxidative cell death. https://www.news-medical.net/news/20241115/Specific-redox-protein-identified-as-a-critical-regulator-of-ferroptosis.aspx https://www.news-medical.net/news/20241115/Specific-redox-protein-identified-as-a-critical-regulator-of-ferroptosis.aspx#comment https://www.news-medical.net/post.aspx?id=55f6fa50-b5b7-443c-9a79-43ac7b32c00e Fri, 15 Nov 2024 21:46:00 -0500 The rod-shaped tuberculosis (TB) bacterium, which the World Health Organization has once again ranked as the top infectious disease killer globally, is the first single-celled organism ever observed to maintain a consistent growth rate throughout its life cycle. https://www.news-medical.net/news/20241115/TB-pathogens-surprising-growth-mechanism-challenges-bacterial-biology.aspx https://www.news-medical.net/news/20241115/TB-pathogens-surprising-growth-mechanism-challenges-bacterial-biology.aspx#comment https://www.news-medical.net/post.aspx?id=8caeac79-0ced-4a48-996f-293e73d94e0a Fri, 15 Nov 2024 18:39:00 -0500 During the COVID-19 pandemic, genomic surveillance proved vital in helping understand the evolution and spread of the SARS-CoV-2 virus. https://www.news-medical.net/news/20241115/Genomic-surveillance-could-revolutionize-the-fight-against-antimicrobial-resistance.aspx https://www.news-medical.net/news/20241115/Genomic-surveillance-could-revolutionize-the-fight-against-antimicrobial-resistance.aspx#comment https://www.news-medical.net/post.aspx?id=7070624f-d2fa-4e2c-8b8f-7a092c74cfa3 Fri, 15 Nov 2024 17:37:00 -0500 Scientists at deCODE genetics, a subsidiary of Amgen, and collaborators have published a study in Journal of Allergy and Clinical Immunology reporting a rare missense variant in STAT6 that protects against asthma. https://www.news-medical.net/news/20241115/Rare-STAT6-gene-variant-provides-protection-against-severe-asthma.aspx https://www.news-medical.net/news/20241115/Rare-STAT6-gene-variant-provides-protection-against-severe-asthma.aspx#comment https://www.news-medical.net/post.aspx?id=38692daa-cee8-411f-a556-ed8bc799b0ee Fri, 15 Nov 2024 16:58:00 -0500 A new study presents "Evo" – a machine learning model capable of decoding and designing DNA, RNA, and protein sequences, from molecular to genome scale, with unparalleled accuracy. Evo's ability to predict, generate, and engineer entire genomic sequences could change the way synthetic biology is done. https://www.news-medical.net/news/20241115/Evo-model-set-to-transform-synthetic-biology-and-disease-diagnosis.aspx https://www.news-medical.net/news/20241115/Evo-model-set-to-transform-synthetic-biology-and-disease-diagnosis.aspx#comment https://www.news-medical.net/post.aspx?id=29625ad2-94d6-4b9b-8bb1-66e5d20119c4 Fri, 15 Nov 2024 15:45:00 -0500 Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have uncovered an unexpected role for the molecule netrin1 in organizing the developing spinal cord. https://www.news-medical.net/news/20241115/UCLA-researchers-discover-netrin1s-unexpected-role-in-spinal-cord-development.aspx https://www.news-medical.net/news/20241115/UCLA-researchers-discover-netrin1s-unexpected-role-in-spinal-cord-development.aspx#comment https://www.news-medical.net/post.aspx?id=d68d81e9-c845-448a-921c-5ece14dc8ae9 Fri, 15 Nov 2024 15:10:00 -0500 Most cancer treatments – from chemotherapies to engineered immune cells – have a host of side effects, in large part because they affect healthy cells in the body at the same time as targeting tumor cells. https://www.news-medical.net/news/20241115/Customizable-biological-sensors-activate-cancer-immunotherapy-only-in-tumor-environments.aspx https://www.news-medical.net/news/20241115/Customizable-biological-sensors-activate-cancer-immunotherapy-only-in-tumor-environments.aspx#comment https://www.news-medical.net/post.aspx?id=0de30225-15d3-4398-9f72-008b8945691f Fri, 15 Nov 2024 15:04:00 -0500 A new study has developed an innovative approach to combat antibiotic-resistant bacteria by tagging them with a chimeric agent that activates the immune system towards them. https://www.news-medical.net/news/20241115/Chimeric-tagging-technique-offers-new-hope-in-the-fight-against-drug-resistant-infections.aspx https://www.news-medical.net/news/20241115/Chimeric-tagging-technique-offers-new-hope-in-the-fight-against-drug-resistant-infections.aspx#comment https://www.news-medical.net/post.aspx?id=8af1282d-730b-4837-b4fc-2f12a4ecaacc Fri, 15 Nov 2024 14:49:00 -0500